Androgenetic alopecia and natural products - Wikenfarma

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Alopecia androgenetica e prodotti naturali

Androgenetic alopecia, or baldness, is the most common hair disease. It usually manifests as thinning in the fronto-temporal and vertex area. The term “androgenetic” stands for the fact that this condition has a close dependence with androgen hormones and hereditary genetic factors.

The etymology of the word Androgenetic Alopecia Is derived from:

ANDRO = androgenic hormones (male hormones) e GENETICS = hereditary predisposition.

The most important hormone for the development of baldness is the DIHYDROTESTOSTERONE o DHT which is a potent androgenic hormone. DHT is produced locally in the hair follicle from testosterone that arrives through blood vessels.

Male androgenetic alopecia

Follicles predisposed to androgenetic alopecia produce greater amounts of DHT than follicles that are not affected by the disease. DHT production is regulated by the enzyme 5-Alpha Reductase. In men, Androgenetic Alopecia does not depend on an excess of male hormones, but on increased DHT production at the follicular level.

Therapy for androgenetic alopecia

To counteract androgenetic alopecia, there are many products available on the market. Finasteride drugs provide a selective blockade of 5-Alpha Reductase, but they can sometimes have side effects. Especially at the level of the sexual sphere and at the level of the central nervous system for those already suffering from depression.

Side effects of finasteride on sexuality:

Decreased libido
Reduced orgasm
Erection reduction
Reduction of seminal fluid
Testicular pain

Side effects of finasteride on the central nervous system:

Alteration of brain neurotransmitter levels, so caution should be exercised when therapeutically including finasteride in psychiatric patients or those using drugs that affect the central nervous system.

Serenoa Repens: an effective alternative for Androgenetic Alopecia

Po improve the tolerability profile and long-term therapeutic sustainability with alternatives to drugs, several products containing SERENOA REPENS: a natural but highly effective active ingredient to counteract androgenetic alopecia and selectively block 5-Alpha Reductase.

There are numerous products on the market based on Serenoa Repens, so it is essential to skillfully untangle the jungle of alternatives in pharmacies and on the Internet. In order to be able to choose a product that has definite scientific validity, it is first necessary to get advice from your doctor. Secondly, it is necessary to evaluate not only the absolute value of the amount of Serenoa Repens contained per dosage unit (tablet, capsule, or soft gel), but the titration of the active ingredient.

To make this concept clearer I will give some examples:

Serenoa Repens is extracted from the berries of Sow Palemetto, a palm tree native to Florida. If the DRY EXTRACT is used in a product, it means that the titration in Serenoa Repens is about 40-45%, which is the maximum that raw material companies can guarantee when grinding Sow Palmetto berries. So in a 320 mg capsule of Serenoa Repens titrated at 45%, the active ingredient that performs its anti-androgenic action is about 144mg. For optimal therapeutic efficacy, I need to take at least 2-3 capsules daily to reach at least 300mg of pure serenoa repens, a dosage recommended by published studies and international literature.

In this case, for every 100 mg of raw product there are 45 mg of serenoa repens and 55 mg of terpenes, flavonoids, and other substances that are useless for therapy and often have a poor gastric tolerability profile. In fact, it is not uncommon for those who take 2 or 3 capsules a day of products with Serenoa Repens in dry extract to experience gastro-intestinal discomfort such as nausea, vomiting, diarrhea, and flauto lenza.

The RestaX line

Instead, there are high-profile, high-quality products that contain Serenoa Repens titrated to 90-95%: this is the case, for example, with products for androgenetic alopecia from the Restax line.

RESTX guarantees 300mg of Serenoa Repens per soft gel or pearl. Restax softgels contain pure oil of active Sereneoa Repens in sterol fraction at the highest concentration.

What are the benefits of RestaX softgels?

Softgels contain the optimal daily amount in one pearl (posological unit)
Serenoa Repens is found at the maximum titration commercially available
The Serenoa Repens oil in Restax is in purified sterol fraction, so they do not manifest gastro-intestinal side effects
The softgel, rather than capsule, formulation ensures immediate immediate and maximal absorption and bioavailability compared to the dry extract

What are the innovative aspects of RestaX?

Restax comes in a formulation biphasic: inside the package are 2 blisters containing softgels (pearls) of Serenoa Repens and capsules with the antioxidants, respectively
Capsules with antioxidants provide a reduction in oxidative stress without having to take another product that would aggravate the daily expense and compliace
Xanthine rod and Proanthocyanidins, contained within the caspula, are highly effective antioxidants with a high scientific profile
Restax exhibits excellent efficacy on blocking 5-alpha reductase
Restax shows an excellent tolerability profile
Restax can be taken under strict medical supervision for very long cycles
Restax is easily taken: the softgel and capsule are taken together with the same glass of water in the evening at dinner.