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Keywords: anti-dandruff shampoo, seborrhea, dandruff, scalp, climbazole, zinc lactate, salicylic acid
Scientific study by Dr. Comacchi in the Journal of Plastic and Pathology Dermatology
Wikenfarma research is born and evolves continuously through clinical trials and studies conducted by physicians and universities. Our goal is to ensure the development of specific, targeted products in trichology and dermatology that can adapt to patients’ needs and characteristics.
It is with great honor that we present a clinical study presented by Dr. Claudio Comacchi in the scientific journal JPD (“Journal of Plastic and Pathology Dermatology”) analyzing the efficacy of an anti-dandruff shampoo in fifteen male patients with scalp seborrhea.
Following is an excerpt from the article:
Clinical study on the efficacy of a anti-dandruff shampoo containing climbazole, zinc lactate and salicylic acid for scalp seborrhea in 15 male patients
Introduction
The term seborrhea is understood to mean the excessive production of sebum. Seborrhea or oily skin is a common phenomenon that is rarely diagnosed, perhaps due to the fact that it is considered a normal or otherwise paraphysiological condition. The skin of the seborrheic patient, in areas rich in sebaceous glands, is shiny; the nasogenic folds, forehead, or retro-ear area are oily and greasy to the touch, and patients, especially women, complain of this appearance. The hair is also greasy, difficult to comb, and scales may develop on the erythematous scalp.
If seborrhea is associated with dandruff, with the formation of yellowish, greasy scales, this is called pityriasis steatoides. Especially during the summer period and in hot climates, seborrhea can be a cause of severe discomfort. It is also often accompanied by increased sweating (hyperhidrosis) such that it is difficult to determine whether the main culprit for the unpleasant skin condition is sebum or sweat. In winter months or dry climates the problem appears less prominent. Seborrhea is a predisposing factor toward other dermatoses, such as acne vulgaris, folliculitis, seborrheic dermatitis, and rosacea.
In addition, excessive sebum production sometimes leads to the development of a rancid and unpleasant body odor (bromhidrosis). In the elderly, seborrhea tends to decrease but still the problem may persist throughout life. Emotional factors also play a role. In many cases seborrhea is only a subjective fact and the patient who, for his or her own personal aesthetic evaluation, reports seborrhea in the absence of actual clinical findings of the scalp. Individuals with baldness often complain of scalp oiliness. Both seborrhea and androgenetic defluvium are related to androgenic activity (dihydrotestosterone and androstandiol) but there is no direct connecting contribution between the two conditions. There are individuals with severe seborrhea but never baldness because androgenetic baldness is hereditary.
Genetic predisposition is also the most important factor in determining the degree of seborrhea. Seborrhea and androgenetic defluvium are therefore often simultaneous but are not the consequence of each other. Androgen hormones stimulate sebum production while estrogen reduces it.
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