{"id":19428,"date":"2024-06-14T10:27:47","date_gmt":"2024-06-14T08:27:47","guid":{"rendered":"https:\/\/wikenfarma.com\/clinical-case-in-dermatology-patient-with-bilateral-viligine\/"},"modified":"2025-03-25T09:29:54","modified_gmt":"2025-03-25T08:29:54","slug":"clinical-case-in-dermatology-patient-with-bilateral-viligine","status":"publish","type":"post","link":"https:\/\/wikenfarma.com\/en\/clinical-case-in-dermatology-patient-with-bilateral-viligine\/","title":{"rendered":"CLINICAL CASE IN DERMATOLOGY: PATIENT WITH BILATERAL VILIGINE"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"19428\" class=\"elementor elementor-19428 elementor-11014\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a6f39ed e-flex e-con-boxed e-con e-parent\" data-id=\"a6f39ed\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-b9ce344 e-con-full e-flex e-con e-child\" data-id=\"b9ce344\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-af51156 elementor-widget elementor-widget-heading\" data-id=\"af51156\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">case study<\/h5>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-44b844a elementor-widget elementor-widget-heading\" data-id=\"44b844a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">CLINICAL CASE IN DERMATOLOGY:\nPATIENT WITH BILATERAL VITILIGO  <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2855615 elementor-align-left elementor-widget elementor-widget-post-info\" data-id=\"2855615\" data-element_type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-24195a2 elementor-inline-item\" itemprop=\"author\">\n\t\t\t\t\t\t<a href=\"https:\/\/wikenfarma.com\/en\/author\/wikenfarma\/\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"far fa-user-circle\"><\/i>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-author\">\n\t\t\t\t\t\t\t\t\t\twikenfarma\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-e32289b elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t<a href=\"https:\/\/wikenfarma.com\/en\/2024\/06\/14\/\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"fas fa-calendar\"><\/i>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>June 14, 2024<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8b8356c e-con-full e-flex e-con e-child\" data-id=\"8b8356c\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4ee897c elementor-widget elementor-widget-image\" data-id=\"4ee897c\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.puglieseantonio.com\/\">\n\t\t\t\t\t\t\t<img decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2023\/01\/download-150x150.webp\" class=\"attachment-thumbnail size-thumbnail wp-image-6817\" alt=\"foto dott pugliese\" srcset=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2023\/01\/elementor\/thumbs\/download-qto1twin6x06pp46djqrf36p206vazfu49s9knl2l8.webp 150w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2023\/01\/download-100x100.webp 100w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8c37000 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"8c37000\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong><em>Dr. Pugliese Antonio<\/em><\/strong><br><em>Medical Surgeon<\/em><br><strong><em>Specialist in Dermatology and Venereology<\/em><\/strong><br><em>Castellaneta (TA)<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-03d0011 elementor-widget elementor-widget-text-editor\" data-id=\"03d0011\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Presentation of a clinical case with photographic comparison referring to a pre- and post-therapy period. The Patient under study presented with a case of bilateral vitiligo, with presentation of facial hypopigmentation in the peribuccal and neck area, associated with beard incanutization in the follicles originating from the areas affected by the vitilitic disease.   <\/p><p>The therapeutic choice is turned on the use of <b>VITIwiken<\/b> and <b>VITIwiken cream<\/b> combined with excimer laser phototherapy, this because the anti-inflammatory action of piperine and curcumin have already been shown in previous clinical and scientific studies to be capable of assisting the therapeutic efficacy of phototherapy and leading to improvements in the patient&#8217;s pigmentation status, reducing oxidative stress and allowing melanocytes to return to their physiological activity. Following a treatment of <span style=\"text-decoration: underline;\"><em>4 months<\/em><\/span> visible improvement in the patient&#8217;s pigmentation with increased normally pigmented skin surface was already beginning to be seen. <\/p><p><strong> <\/strong><\/p><p><strong>CLINICAL CASE.<\/strong><\/p><p><strong>Patient:<\/strong> Male, 38 years old<\/p><p><strong>Diagnosis:<\/strong> Bilateral vitiligo on part of the face in the peribuccal area and on the neck<\/p><p><strong>Therapy<\/strong>: <a href=\"https:\/\/wikenfarma.com\/en\/prodotto\/vitiwiken-30cpr\/\"><strong>VITIwiken 30cpr<\/strong><\/a> (1cp\/day in the morning) + <a href=\"https:\/\/wikenfarma.com\/en\/prodotto\/vitiwiken-cream-50ml\/\"><strong>VITIwiken Cream 50mL<\/strong><\/a> (2 applications\/day 9 am and 4 pm, away from sun exposure or phototherapy) + excimer laser phototherapy (wavelength 308nm)<\/p><p><strong>Photos:<\/strong> Before and After 4 months of therapy<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9e2f842 e-grid e-con-full e-con e-child\" data-id=\"9e2f842\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4f6b753 elementor-widget elementor-widget-image\" data-id=\"4f6b753\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/wikenfarma.com\/categoria-prodotto\/area-vitiligine\/\">\n\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"282\" src=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2024\/06\/PUGLIESE-BILATERALE-1-2-300x282.webp\" class=\"attachment-medium size-medium wp-image-11020\" alt=\"\" srcset=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2024\/06\/PUGLIESE-BILATERALE-1-2-300x282.webp 300w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2024\/06\/PUGLIESE-BILATERALE-1-2.webp 306w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Prima della terapia<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dd25461 elementor-widget elementor-widget-image\" data-id=\"dd25461\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t<figure class=\"wp-caption\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/wikenfarma.com\/categoria-prodotto\/area-vitiligine\/\">\n\t\t\t\t\t\t\t<img decoding=\"async\" width=\"300\" height=\"288\" src=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2024\/06\/PUBLIESE-BILATERALE-2-1-300x288.webp\" class=\"attachment-woocommerce_thumbnail size-woocommerce_thumbnail wp-image-11019\" alt=\"\" \/>\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<figcaption class=\"widget-image-caption wp-caption-text\">Dopo 4 mesi<\/figcaption>\n\t\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a5b7e9f elementor-widget elementor-widget-text-editor\" data-id=\"a5b7e9f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><i><span style=\"font-weight: 400;\">Dr. Antonio Pugliese<\/span><\/i><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e430cfc elementor-widget elementor-widget-heading\" data-id=\"e430cfc\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Share the article on your 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wp-image-3498\" alt=\"vitiwiken\" srcset=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2021\/12\/thumbnail-wikenfarma-9.webp 500w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2021\/12\/thumbnail-wikenfarma-9-300x300.webp 300w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2021\/12\/thumbnail-wikenfarma-9-150x150.webp 150w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2021\/12\/thumbnail-wikenfarma-9-100x100.webp 100w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/figure><div class=\"elementor-image-box-content\"><h5 class=\"elementor-image-box-title\"><a href=\"https:\/\/wikenfarma.com\/en\/prodotto\/vitiwiken-30cpr\/\">VITIwiken 30cpr<\/a><\/h5><p class=\"elementor-image-box-description\">VITIwiken is a high antioxidant supplement that physiologically contributes to inhibiting pro-inflammatory pathways<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-483014c elementor-position-left elementor-position-left elementor-vertical-align-top elementor-vertical-align-top elementor-widget elementor-widget-image-box\" data-id=\"483014c\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><a href=\"https:\/\/wikenfarma.com\/en\/prodotto\/vitiwiken-cream-50ml\/\" tabindex=\"-1\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"500\" src=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2021\/07\/Vitiwiken-crema-11-removebg-preview.png\" class=\"attachment-full size-full wp-image-15847\" alt=\"\" srcset=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2021\/07\/Vitiwiken-crema-11-removebg-preview.png 500w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2021\/07\/Vitiwiken-crema-11-removebg-preview-300x300.png 300w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2021\/07\/Vitiwiken-crema-11-removebg-preview-150x150.png 150w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2021\/07\/Vitiwiken-crema-11-removebg-preview-100x100.png 100w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/a><\/figure><div class=\"elementor-image-box-content\"><h5 class=\"elementor-image-box-title\"><a href=\"https:\/\/wikenfarma.com\/en\/prodotto\/vitiwiken-cream-50ml\/\">VITIwiken Cream<\/a><\/h5><p class=\"elementor-image-box-description\">VITIwiken Crema is a cream with high antioxidant power that contributes topically to promote repigmentation of areas affected by vitiligo<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Case report by Dr. Pugliese on a patient with bilateral facial vitiligo and treated with VITIwiken 30cpr and VITIwiken Cream.<\/p>\n","protected":false},"author":1,"featured_media":18529,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[265,270,271],"tags":[],"class_list":["post-19428","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog-en","category-medical-blog","category-medical-blog-clinical-cases"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>CLINICAL CASE: Patient with Bilateral Vitiligo on the face.<\/title>\n<meta name=\"description\" content=\"Case report by Dr. Pugliese on a patient with bilateral facial vitiligo and treated with VITIwiken 30cpr and VITIwiken Cream.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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