{"id":18963,"date":"2022-04-27T12:10:05","date_gmt":"2022-04-27T10:10:05","guid":{"rendered":"https:\/\/wikenfarma.com\/diviken-spray-observational-study\/"},"modified":"2025-03-21T15:24:26","modified_gmt":"2025-03-21T14:24:26","slug":"diviken-spray-observational-study","status":"publish","type":"post","link":"https:\/\/wikenfarma.com\/en\/diviken-spray-observational-study\/","title":{"rendered":"DIVIKEN SPRAY OBSERVATIONAL STUDY"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"18963\" class=\"elementor elementor-18963 elementor-4489\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8f8de7e elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8f8de7e\" data-element_type=\"section\" data-settings=\"{&quot;shape_divider_top&quot;:&quot;triangle&quot;,&quot;shape_divider_top_negative&quot;:&quot;yes&quot;,&quot;animation&quot;:&quot;none&quot;}\">\n\t\t\t\t\t<div class=\"elementor-shape elementor-shape-top\" data-negative=\"true\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 1000 100\" preserveAspectRatio=\"none\">\n\t<path class=\"elementor-shape-fill\" d=\"M500.2,94.7L0,0v100h1000V0L500.2,94.7z\"\/>\n<\/svg>\t\t<\/div>\n\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-66ba66b7\" data-id=\"66ba66b7\" data-element_type=\"column\" data-settings=\"{&quot;animation&quot;:&quot;none&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6b33db9 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"6b33db9\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInLeft&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Keywords<\/strong>: vitamin D, vitamin D3, vitamin deficiency, supplement<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5e28d22e elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"5e28d22e\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInDown&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">DIVIKEN SPRAY OBSERVATIONAL STUDY<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2009d66 elementor-invisible elementor-widget elementor-widget-heading\" data-id=\"2009d66\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInDown&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Raffaele Iandoli, Domenico Iandoli<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4262d2ec elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4262d2ec\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-314ebdd8\" data-id=\"314ebdd8\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6dcdd218 elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"6dcdd218\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInLeft&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Introduction<\/strong><\/p><p>Vitamin D activation occurs in the skin during exposure to sunlight. Consequently, increased exposure to the sun results in increased levels of the vitamin. Although living in Southern Europe, numerous studies indicate that vitamin D levels in the Italian population are insufficient overall.<br>To verify this finding, 48 patients requesting a dermatological examination for various diseases were selected and, after informing them of the reason for the examination, vitamin D dosage was requested.<br>In case of vitamin deficiency, specific therapy was initiated.<br>The results that emerged from the investigation are presented.  <\/p><p><strong>Type of patients, materials and methods<\/strong><\/p><p>Forty-eight patients who came to our observation for various dermatological conditions were selected.<br>Patients were selected on the basis of booking order and not on the basis of either dermatologic or systemic diseases.<br>The ages of the 20 female patients ranged from 19 to 80 years old, while the 28 male patients ranged from 18 to 80 years old.<br>After informing the patients of the purpose of the investigation, we prescribed the blood dosage of vitamin D3.<br>In cases of vitamin deficiency, Diviken spray was prescribed at a daily dose of 4 sprays in the oral cavity. In cases of vitamin D3 values between 12 and 30 ng\/ml, the daily dose was set at 8 sprays per day. After three months, patients underwent a new blood sampling to check the achieved level of the vitamin.  <\/p><p><strong>Exclusion criteria<\/strong><\/p><p>Patients under the age of 18 years, and patients with known allergy to the components of the<br>drug were excluded.<\/p><p><strong>Results<\/strong><br>All patients presented vitamin deficiency.<br>Therapy was then initiated at the necessary dosage in relation to the blood value of vitamin D3.<br>After three months of therapy, normalization of the blood Vitamin D3 level was observed.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-97fae2c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"97fae2c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-48fae83\" data-id=\"48fae83\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f569cec elementor-widget elementor-widget-image\" data-id=\"f569cec\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"633\" height=\"371\" src=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico1-studio-iandoli.webp\" class=\"attachment-large size-large wp-image-4493\" alt=\"\" srcset=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico1-studio-iandoli.webp 633w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico1-studio-iandoli-300x176.webp 300w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico1-studio-iandoli-600x352.webp 600w\" sizes=\"(max-width: 633px) 100vw, 633px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f6dc92a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f6dc92a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-8fb4542\" data-id=\"8fb4542\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-55c0da5 elementor-widget elementor-widget-image\" data-id=\"55c0da5\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"395\" height=\"232\" src=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico4-studio-iandoli.webp\" class=\"attachment-large size-large wp-image-4497\" alt=\"\" srcset=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico4-studio-iandoli.webp 395w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico4-studio-iandoli-300x176.webp 300w\" sizes=\"(max-width: 395px) 100vw, 395px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-ffc0c24\" data-id=\"ffc0c24\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8803b23 elementor-widget elementor-widget-image\" data-id=\"8803b23\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"397\" height=\"249\" src=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico5-studio-iandoli.webp\" class=\"attachment-large size-large wp-image-4496\" alt=\"\" srcset=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico5-studio-iandoli.webp 397w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico5-studio-iandoli-300x188.webp 300w\" sizes=\"(max-width: 397px) 100vw, 397px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b6a0a71 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b6a0a71\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-5bbda0b\" data-id=\"5bbda0b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7591073 elementor-widget elementor-widget-image\" data-id=\"7591073\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"398\" height=\"247\" src=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico2-studio-iandoli.webp\" class=\"attachment-large size-large wp-image-4495\" alt=\"\" srcset=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico2-studio-iandoli.webp 398w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico2-studio-iandoli-300x186.webp 300w\" sizes=\"(max-width: 398px) 100vw, 398px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2f7adc0\" data-id=\"2f7adc0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4a45e42 elementor-widget elementor-widget-image\" data-id=\"4a45e42\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"396\" height=\"243\" src=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico6-studio-iandoli.webp\" class=\"attachment-large size-large wp-image-4494\" alt=\"\" srcset=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico6-studio-iandoli.webp 396w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico6-studio-iandoli-300x184.webp 300w\" sizes=\"(max-width: 396px) 100vw, 396px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-fd737ad elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"fd737ad\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-b639492\" data-id=\"b639492\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a5b3d5d elementor-widget elementor-widget-image\" data-id=\"a5b3d5d\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"405\" height=\"242\" src=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico7-studio-iandoli.webp\" class=\"attachment-large size-large wp-image-4492\" alt=\"\" srcset=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico7-studio-iandoli.webp 405w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico7-studio-iandoli-300x179.webp 300w\" sizes=\"(max-width: 405px) 100vw, 405px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-f9322bd\" data-id=\"f9322bd\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a81675e elementor-widget elementor-widget-image\" data-id=\"a81675e\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"404\" height=\"248\" src=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico3-studio-iandoli.webp\" class=\"attachment-large size-large wp-image-4491\" alt=\"\" srcset=\"https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico3-studio-iandoli.webp 404w, https:\/\/wikenfarma.com\/wp-content\/uploads\/2022\/04\/grafico3-studio-iandoli-300x184.webp 300w\" sizes=\"(max-width: 404px) 100vw, 404px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-37586ea elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"37586ea\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-0035c9b\" data-id=\"0035c9b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4a4a02f elementor-invisible elementor-widget elementor-widget-text-editor\" data-id=\"4a4a02f\" data-element_type=\"widget\" data-settings=\"{&quot;_animation&quot;:&quot;fadeInLeft&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>Discussion<\/strong><\/p><p>Despite living in a sunnier region of Europe than the others, even remarkably low levels of vitamin D3 were found in 48 randomly selected patients.<br>In addition to particular dietary variations that are leading us to abandon the Mediterranean diet, traditional in our southern regions, in favor of a U.S. diet, which is certainly faster but low in healthy trace elements and vitamins, we must also consider that normal clothing protects the skin from exposure to the sun. It is therefore like having a solar panel that is kept constantly covered.<br>Vitamin D3 is essential for the normal performance of many of our body&#8217;s metabolic cycles. Since we cannot change social habits, it seems appropriate to intervene pharmacologically, after hematochemical evaluation, by choosing a drug that is easy to take, free of unpleasant odor and with an acceptable taste, administered daily, which appears pharmacologically more useful than single monthly loading doses, in order to ensure the best possible health conditions for our patients.  <\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-53ba14ad elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-invisible\" data-id=\"53ba14ad\" data-element_type=\"section\" data-settings=\"{&quot;shape_divider_bottom&quot;:&quot;triangle&quot;,&quot;shape_divider_bottom_negative&quot;:&quot;yes&quot;,&quot;animation&quot;:&quot;fadeInUp&quot;}\">\n\t\t\t\t\t<div class=\"elementor-shape elementor-shape-bottom\" data-negative=\"true\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" viewBox=\"0 0 1000 100\" preserveAspectRatio=\"none\">\n\t<path class=\"elementor-shape-fill\" d=\"M500.2,94.7L0,0v100h1000V0L500.2,94.7z\"\/>\n<\/svg>\t\t<\/div>\n\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6583acf3\" data-id=\"6583acf3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Observational study Diviken Spray by Dr. Iandoli Raffaele and Dr. Iandoli Domenico on behalf of WIkenfarma, find out&#8230;<\/p>\n","protected":false},"author":1,"featured_media":17976,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[265,270,271],"tags":[],"class_list":["post-18963","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog-en","category-medical-blog","category-medical-blog-clinical-cases"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.7 - 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