TRIVIS WOMEN’S LOTION is a topical hair lotion formulated for the purpose of nourishing hair bulbs, reducing inflammation and stimulating hair regrowth in patients with female alopecia in both childbearing and post-menopausal age, thus performing a triple synergistic action.

Female alopecia is mainly regarded as an estrone deficiency and, by virtue of this, TriVis Women’s Lotion contains phytoestrogens, which may exert estrogen-like action at the hair level. These phytoestrogens are present In soybean seed extract., of which they constitute the main bioactive component.

Specifically, in fact, the Trivis Women’s Lotion consists of the following:

• Soybean seed extract: Soybeans contain appreciable amounts of vitamins, carbohydrates, lipids and minerals, but the most chemically interesting substances in the extract are isoflavones. They act as phytoestrogens, with weak estrogenic activity, by increasing the amount of SHBG (carrier protein for sex hormones) circulating in the blood locally, which in fact binds and transports them as if they were estrogen. One of these phytoestrogens, daidzein, after being converted to its active form, exerts an anti-androgenic action by reducing hair loss due to DHT.
• Xylose: It performs a dual function, both nutritive at the level of the hair bulb cells and thermo-protective on the hair itself, being in fact a simple sugar that can be absorbed and metabolized by the hair bulb stem cells, helping them in their hair production activity. This sugar also binds to the keratin that makes up the hair, protecting it from denaturation due to heat
• Melatonin: It performs an important function in the hair life cycle in that it is able to limit apoptosis at the hair level and increase gene expression of estrogen receptors for scalp stem cells, thereby enhancing the bonds between scalp cells and estrogen. This, consequently stimulates hair growth Lengthening the Anagen phase. Hair loss can also often originate from. melatonin deficiencies.
• Sphinganine: It is a key aminoalcohol constituent of sphingolipids, important molecules found in all cell membranes. It acts on hair by balancing its life cycle, lengthens the anagen phase and strengthens the hair follicle.
• 18β-glycyrrhetinic acid: It is extracted from licorice and is a natural anti-inflammatory, since it has a chemically similar structure to that of endogenous cortisone. Because of this, in fact, it is able to bind to cellular receptors for glucocorticoids, helping to regulate blood pressure, blood sugar, and interrupting the inflammatory response.
• Caffeine: It performs both an anti-androgenic action, inhibiting 5-alpha-reductase type 1 at the scalp level, and stimulating hair growth, lengthening the anagen phase. Caffeine in fact Promotes the influx of nutrients to hair bulb cells by assisting the mitotic activity of hair stem cells.
• Sorbitol: Sorbitol is a polyalcohol, of similar behavior to glucose from which it is obtained by chemical reduction. Used in cosmetics as a humectant, for preserve from dehydration and as a moisturizing agent to prevent skin and scalp dryness, counteracting the dehydrating effects of the hydroalcoholic base of the lotion.